Creatine Case Study

Case Study


Learning Goals /
Concept Map

Creatine and Related Compounds


Amino Acids

Creatine in the Body


Creatine-Creatinine Equilibrium

Creatinine Test for Kidney Function


Regulation and Ethics

Amine & Nitrile Chemistry

Laboratory Synthesis

Chemical Analysis

Creatine-Phosphocreatine Equilibrium

Uses & Side Effects


Creatine is synthesized naturally in the liver, pancreas, and kidneys from three amino acids:  glycine, arginine, and methionine.[1,2]  Learn more about AMINO ACIDS.


[1] Clark, Joseph F. “Creatine and Phosphocreatine: A Review of Their Use in Exercise and Sport.” Journal of Athletic Training. 1997, 32(1), 45-50.
[2] Juhn, Mark S. “Oral Creatine Supplementation: Separating Fact from Hype.” The Physician and Sports Medicine. 1999, 27(5).